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If youre a smoker, it could be down to nicotine, which triggers your adrenal glands and boosts your adrenaline

Rostami-Hodjegan A, Amin AM, Spencer EP, Lennard MS, Tucker GT, Flanagan RJ (2004) Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patients

RYO cigarettes are clearly the better choice if you need a cigarette for any of the above purposes because they are a cheaper and healthier alternative to commercial cigarettes