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With this study, we have found that people who smoke a pack a day develop an average of 150 extra mutations in their lungs every year, which explains why smokers have such a higher risk of developing lung cancer. Additionally, other organs were also affected and the study showed that a pack a day led to an estimated average 97 mutations in each cell in the larynx, 39 mutations for the pharynx, 23 mutations for the mouth, 18 mutations for the bladder, and 6 mutations in every cell of the liver each year

And with a company of twenty-one actors (with practically no doubling), aided by four deftly utilized musicians, its a pleasure to see a show presented in a style that most producers balk at due to the extravagant costs involved, especially for a straight play

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Paul Grundy, the chief medical officer, said: "It is an addiction - they're here, often at the most stressful time in their lives, so we know this is a big ask