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Prior research indicates that reducing nicotine content could help smokers quit, but there is little evidence to demonstrate if these policies could adversely affect smokers with current or prior affective disorders like depression and anxiety disorders which affect an estimated 38% of U.S

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On January 26, 2023, the FDA announced that it will not regulate CBD as a dietary supplement or food stating that it is not apparent how CBD products could meet safety standards for dietary supplements or food additives

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