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As the pieces get smaller enough, they'll fall through the holes and into the bottom chamber

Interestingly, recent paper showed that thyroid hormone treatment attenuates bleomycin-induced lung fibrosis development via reducing alveolar epithelial cell apoptosis, which can be at least partly attributed to PGC-1-mediated mitochondrial biogenesis accompanied by normalized mitochondrial morphological integrity [36]

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Leite FRM, Nascimento GG, Scheutz F, et al