cigarette smoking can cause CIGARETTES CANCER HEALTH WARNINGS GOVERNMENTS TOBACCO Tobacco Fact File

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Maternal smoking during pregnancy has been shown to alter umbilical cord blood DNA methylation in various genes such as aryl-hydrocarbon receptor repressor ( AHRR ), cytochrome P450 family 1 subfamily A member 1 ( CYP1A1 ), growth factor-independent 1 transcriptional repressor ( GFI1 ), and myosin IG ( MYO1G ) 30,31

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One study in psoriasis showed no difference in therapeutic response between smokers and non-smokers when assessed at 3-, 6-, and 12-month timepoints of ustekinumab treatment [27]

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