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Neither showed any effect on the primary endpoint, the Clinical Dementia Rating-Sum of Boxes at 104 weeks, nor on secondary cognitive and functional scales, and a pooled analysis found no delay in progression from mild cognitive impairment to dementia (hazard ratio 0.96) [1]

A cross-over study of the acute effects of espresso coffee on glucose tolerance and insulin sensitivity in people with type 2 diabetes mellitus

Abstract Metabolic flexibility describes the ability of cells to respond or adapt its metabolism to support and enable rapid proliferation, continuous growth, and survival in hostile conditions