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Furthermore, the potential synergistic or antagonistic effects among diverse smoke compounds were not accounted for

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Of these diseases, malaria was (and still is in many parts of the world where DDT use was not widespread) the most insidious killer of human beings throughout history and many of us would not be alive today were it not for the eradication of malaria in these parts of the world through the wide use of DDT

If the levels of nicotine in cigarettes were reduced to levels that were not addictive, young individuals who have an interest in smoking might never develop a dependence on cigarettes, the leading cause of morbidity and premature mortality in the USA [3]