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When modeling the financial impact of GLP-1 coverage, including potential offsets in cardiometabolic claims, plan sponsors should consider both the high per-member-per-month drug cost and the likelihood that weight and risk factors will revert to baseline after medications are discontinued

Jha D, Mitra Mazumder P (2019) High fat diet administration leads to the mitochondrial dysfunction and selectively alters the expression of class 1 GLUT protein in mice

The glucagon-like peptide-1 (GLP-1) agonists liraglutide and Ex-4 activated the expression of peroxisome proliferator-activated receptor alpha (PPAR) via a GLP-1 receptor-dependent 5 AMP-activated protein kinase pathway

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