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Available data increasingly point to the risk that e-cigarettes may actually widen existing health inequalities, especially if their use becomes normalised in low-income or marginalised communities without accompanying structural support [52, 54, 112]
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FDA has also published the Required Warnings for Cigarette Packages and Advertisements Small Entity Compliance Guide to help small businesses understand and comply with the final rule
In reality, however, the physiologic threat is that nicotine affects mood, creates dependence, and causes withdrawal symptoms during cessation attempts
However, in early 2015 a paper appeared in the BMJ which indicated that Chantixs neuropsychiatric adverse effects might be overstated
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