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Immune System Dysfunction: RA occurs when the immune system mistakenly targets the lining of the joints, triggering inflammation

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Single-cell RNA sequencing studies in murine smoke models have identified an excessive influx of monocyte-derived macrophage subset population responsible for heightened inflammation and ECM remodeling, a finding that has also been validated in emphysematous COPD patients 59

Another point of concern is the shortage of labor in the field, especially during harvesting, which puts pressure on production costs