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In an article in Cell Systems, a multidisciplinary team at the Wyss Institute for Biologically Inspired Engineering at Harvard University describes an instrument they engineered that can breathe in and out, actively smoke regular and electronic cigarettes much like a human, and deliver the smoke to microfluidic organs-on-chips lined by human lung small airway cells isolated from non-smokers or COPD patients

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the mixture is laid into molds for creating stacks of sheet filter tow, or onto a moving belt or production line to form large continuous rolls of filter tow

Engaging patients in health care decisions in the emergency department through shared decision-making: a systematic review

To fill the tank, it's usually a matter of unscrewing the top connector