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released the Frank Statement to Cigarette Smokers. In the piece, the tobacco companies denied the link to cancer, stating: We believe the products we make are not injurious to health. They sought to cast doubt on the independent studies findings related to lung cancer, saying There is no proof that cigarette smoking is one of the causes. Research suggests, however, that tobacco companies knew by the mid-1950s that their products were linked to cancer and were addictive

In large doses nicotine is highly toxic

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The New York Times reported: The FDA said it did not appear that the IQOS devices, which will be sold with Marlboro-branded regular and menthol sticks, would appeal to younger people