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First and foremost, safety concerns are paramount

Tobacco products are truly global, and various cultures around the world have developed their own methods of consuming it some quite normal, some quite bizarre

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3.1 The unique burden of oral cancer in south Asia: smokeless tobacco South and Southeast Asia, which report the highest incidence and mortality rates for this disease, represent some of the strongest examples of how cultural practices and product types shape oral cancer risk (25)

The secondary type is associated with underlying conditions such as diabetes