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Nicotine also increases blood viscosity, which raises the risk of thrombosis

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Most countries do not have a history of measuring heated tobacco product use, and their reliability and comparability may suffer from methodological challenges, which may include: Inconsistent questions about cigarette smoking compared to use of new tobacco and nicotine products, Ability to differentiate between regular use and trial, Absence of agreed-upon terminology around new tobacco and nicotine products that is understood by survey respondents, and Sample sizes that may be sufficient to measure cigarette smoking prevalence and patterns of use but insufficient to achieve the same objective with adequate precision for new products with much lower number of users