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18mg/ml freebase equates to approximately 6-12 cigarettes per 1ml of vape juice consumed

The Centers for Disease Control and Prevention has documented the respiratory consequences of e-cigarette aerosol inhalation broadly, but nasal-specific toxicology is a less developed area of research, which means the absence of data is not reassurance of safety

The dose is then gradually increased

We cannot let down our guard considering the large percentage of youth e-cigarette users who reported frequent or daily use, reinforcing the challenges they are facing with nicotine dependence. The national survey found that more than one in four of youth e-cigarette users are using the product daily and more than one in three said they had used e-cigarettes in at least 20 of the last 30 days

Colorado has emerged as a leading example