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Gastrointestinal (GI) events are well-known side effects of the GLP-1 class, Novo Nordisk said in a statement

Retatrutide continues producing weight loss beyond the 24-week mark, suggesting that appetite-related effects also continue deepening or at minimum remain stable

The following sources give you the unfiltered picture - clinical evidence, regulatory context, and safety data straight from the organizations that publish it: FDA.gov - official FDA communications on compounded semaglutide, tirzepatide, and the 503B Bulks List proposal (April 30, 2026)

Raza, M

For most folks, that means their GLP-1 medication is stored in the kitchen fridge