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Am J Epidemiol

Drugs like Opdivo, Yervoy, and Keytruda are approved for treating mesothelioma

29 The convergence of these danger signals informs the DC about inhaled material that poses an immediate threat to pulmonary tissues and activates a maturation program: DCs process sampled antigen, present it on major histocompatibility (MHC) molecules, and strongly increase T-cell costimulatory molecule expression on their surface

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But that amount has steadily declined since, and in 2023, total cigarette tax revenue was about $365 million, down 34 percent from 2019