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While the rate of acetylation does not significantly impact the drugs effectiveness, it may result in elevated levels of INH in the bloodstream and a higher occurrence of ADRs

Saleh RA, Agarwal A, Sharma RK, Nelson DR, Thomas AJ

The nicotine concentration in e-liquids is legally limited to 20 mg/ml in the European Union while e-liquids usually contain significantly more nicotine in the USA 14,15

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