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Goepfert did not recommend surgery

A lot of research has been done on NRT

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We propose to compare how strongly different physical activity intensity measures predict the occurrence of new cardiovascular disease events (heart attacks, heart failure, stroke) and mortality, as well as several indicators underlying cardiovascular health including traditional risk factors like blood cholesterol levels, newer blood measures of heart injury (cardiac troponin, natriuretic peptide, galactin-3), changes in heart rate regulation (heart rate variability) and tests of physical functioning

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