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As the authors note, "Understanding what leads to the differences between these types of studies is important to optimize the public health potential and ways to deliver these interventions." Per the PLOS One study, "evidence from NRT studies suggests that discontinuation of a cessation product is often associated with relapse to smoking." As in nicotine lozenge studies where the treatment period was 6 months, imagine declaring victory while the chemical stimulating the active groups brain dopamine pathways is still circulating in their bloodstream

Surgeon Generals Report North American Quitline Consortium Quick Facts on the Risks of E-cigarettes for Young People CDC Quit Smoking and Vaping Truth Initiative Smokefree National Institutes of Health Smoking Cessation: Fast Facts CDC Talk to Your Child About Vaping American Lung Association Teen Smoking: 10 Ways to Keep Teens Smoke-Free Mayo Clinic What Do We Know About E-cigarettes

doi: 10.1136/tobaccocontrol-2014-052057 13

Still, the profile packs a punch