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Both Zepbound (tirzepatide) and Wegovy (semaglutide GLP-1) typically begin to show noticeable effects on appetite and weight within the first month of treatment

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J Clin Endocrin Metab, 91(12):5013-8

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PubMed Central, Lin, Donna Shu-Han, et al

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To my knowledge, there arent any studies looking at the relationship between fertility and using semaglutides

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Conditional inactivation of limbic neuropeptide Y-1 receptors increases vulnerability to diet-induced obesity in male mice

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