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Nicotine promotes angiogenesis, cell proliferation, epithelial-mesenchymal transition, vascular remodeling and dysfunction, inflammation, and oxidative stress in vascular smooth muscle cells causing atherosclerosis, dendritic cell morphology changes, and neuronal signaling, which may lead to mental disorders like depression, addiction, and attention deficit (4653)

Taking breaks and staying hydrated helps prevent this

Despite a decline in overall e-cigarette use in 2020, it remains exceedingly popular among tobacco-naive middle and high school aged adolescents, and the Centers for Disease Control and Prevention notes that youth e-cigarette use remains an epidemic [4]

Drinking water can also help you manage nicotine cravings by mimicking the hand-to-mouth ritual of smoking

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