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The CCL5-CCR1/CCR5 axis maintains crosstalk between BC cells and TAMs and VCAM-1 upregulation increases the binding of TAMs and BC cells during infiltration, which enhances the survival rate of metastatic BC cells during lung colonization

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Acute retroviral syndrome may occur with non-specific symptoms like tiredness, muscle pain, skin rash, headache, sore throat, swollen lymph nodes, joint pain, night sweats, and diarrhoea