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Tobacco blend analysis Tobacco blends used in the ECs described in this work were analysed for nicotine, sugars, total and protein nitrogen, polyphenols, metals, TSNAs, and benzo[a]pyrene (Additional file1: Table S6)

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For some smokers, the ritual of having a cigarette can psychologically signal the body to prepare for a bowel movement, especially if they have associated smoking with bathroom breaks over time