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Janeiro, M.H., Ramrez, M.J., Milagro, F.I., Martnez, J.A., & Solas, M

Researchers should weigh this uncertainty against their individual risk tolerance

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UK guidance typically recommends: Loading doses of colecalciferol (e.g., total of approximately 300,000 IU over 6-10 weeks) for confirmed deficiency Maintenance therapy with 8002,000 IU daily thereafter Higher doses may be required for malabsorption conditions Before starting high-dose vitamin D, check corrected calcium and renal function