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optimal positioning and saliva management increase bioavailability whilst excessive swallowing reduces it

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Brown urine Dark brown pee is usually a sign that you're dehydrated, but it can also be caused by several other things, including: Certain medications, including metronidazole (Flagyl), nitrofurantoin (Furadantin), chloroquine (Aralen), senna-based laxatives, methocarbamol (Robaxin), phenytoin (Dilantin, Phenytek), and certain statins Eating fava beans, rhubarb, or aloe in large quantities Some health problems, including liver and kidney problems, internal bleeding, and porphyria (a group of rare disorders caused by the buildup of natural chemicals called porphyrins) Black urine Black urine is caused by a rare condition called alkaptonuria