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In this review, we comprehensively describe and discuss the impact of acetaldehyde, acrolein, and formaldehyde on mitochondrial function and content and the molecular pathways controlling this (biogenesis versus mitophagy) in epithelial cells of the airways and lungs

Macrophages pigmented smokers macrophages in respiratory bronchioles and neighbouring alveoli, containing granular, yellow-brown cytoplasmic pigments References and Links Barnes P , Mechanisms in COPD compared with asthma semantic Scholar Benjamin, R MD, MBA VADM, USPHS, Surgeon GeneralExposure to Tobacco Smoke Causes Immediate Damage: A Report of the Surgeon General Bohadana A et al Mechanisms of chronic airway obstruction in smokers Respiratory Medicine Volume 98, Issue 2, February 2004, Pages 139-151 TCV