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The FDA, the Federal Trade Commission (FTC), and the public health community at large have determined that the yield method of nicotine measurement is wholly unreliable and gives no indication of actual nicotine intake because smokers engage in compensatory behavior by smoking more cigarettes when using low nicotine yield cigarettes and do not actually achieve reduced nicotine intake

The review also found possible links between vaping and poor oral health, such as dry mouth, gum pain and cracked teeth

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