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Targeting hypoxia within the TME holds promise for enhancing the efficacy of cancer immunotherapies and improving patient outcomes

To burnish their nicotine-stained image throughout the latter half of the 20th century and beyond, British cigarette companies became patrons of the arts and universities, as well as major sponsors of televised sporting events

Anyone could smoke a cigarette, rich and poor alike, but to stand apart, to make a statement about personality and class, users enlivened the paper-wrapped tobacco with a variety of accessories: cigarette cases, ashtrays, lighters, match safes, and of course, most visibly, the holder

It was not until the 1950s that Dr

and (iii) other factors beyond the control of the Company