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14.2%), and adults aged 25-44 years (22.5%) had the highest level by age, followed by those aged 45-64 years (21.3%), 18-24 years (18.3%), and 65 years or older (11%)

The nicotine concentrations in SLT products ranged from 4.67 to 28.23 mg/g (Table 1), average was 12.84 and the coefficient of variation was 83.96%, The unprotonated nicotine was calculated by putting the product pH and appropriate Pka into the Henderson-Haselbalch equation 29 it ranged from 0.10 to 99.1% and the coefficient of variation was 71.38%, indicating great heterogeneity across brands

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Effects of smoking on systemic and intrarenal hemodynamics: influence on renal function