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Acknowledgments The authors would like to express their sincere gratitude to Hao Wang, Cankun Zhou, Yonglian Chen, Jun Lyu, Minqing Feng, and Xiaobin Huang for their valuable contributions to the early stages of this work and for their collaborative support throughout the research process

These were predominantly mild to moderate and occurred mainly during dose escalation

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Intramuscular injections (IM) directly deliver vitamins, minerals, and amino acids into the muscle, allowing for better absorption and faster results than oral supplements

therefore, subsequent analyses were performed in these cell lines