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Lead author Dr Sarah Jackson (UCL Institute of Epidemiology & Health Care) said: The public health impact of this substantial rise in vaping among people who have never regularly smoked will depend on what these people would otherwise be doing

Consequently, mutation or inactivation of Rb can encourage apoptosis

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Biological and genetic factors128 There is evidence that youth may be sensitive to nicotine and that teens can feel dependent on nicotine sooner than adults

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