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[Learn More in MedlinePlus] Code History FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026 FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025 FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024 FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023 FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022 FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021 FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020 FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019 FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018 FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017 FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016

This pre-metastatic niche promotes the release of STAT3-activated lipocalin 2 (LCN2), a secretory glycoprotein from the N2-neutrophils, and induces mesenchymal-epithelial transition of tumor cells thereby facilitating colonization and metastatic outgrowth