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Several significant metabolite-microbe relationships were also revealed, including the glycine strong positive association with Clostridium (Zhuang et al., 2018) and homocysteine positive correlation with Lachnospira , Clostridium , and Haemophilus and its negative correlation with Corynebacterium and Lachnospiraceae (Zhuang et al., 2018)

So if people feel more energetic on GLP-1, its usually an indirect effect , not a direct one

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Notably, lithium, the mood-stabiliser and frontline treatment for bipolar disorder, increases CaMKK2 activity by blocking GSK3-mediated phosphorylation of the S3-node [33]