Mortality was 36.8% in the SJS subgroup and higher in the TEN subgroup at 44.4% (4/9), consistent with the higher lethality of TEN reported in previous studies ( The median latency to onset was 9 days (interquartile range [IQR] 314.5 days) for the overall cohort, 14 days (IQR 321) for SJS, and 10 days (IQR 420) for TEN
Could one class of drugs treat them all
Were doing things with these drugs that dont mimic the biology, said Seeley
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For example, a frequently used substrate to study TGM2, carbobenzoxy-L-glytaminylglycine, has a K m of 22 mM (Folk and Cole, 1965)