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Other harmful effects: Heart problems

The adolescents most likely to begin to use tobacco and progress to regular use are those who have lower academic achievement.1 The evidence is sufficient to conclude that there is a causal relationship between peer group social influences and the initiation and maintenance of smoking behaviors during adolescence.1 Affective processes play an important role in youth smoking behavior, with a strong association between youth smoking and negative affect.1 The evidence is suggestive that tobacco use is a heritable trait, more so for regular use than for onset

However, in human sperm, around 15% of the DNA is still bound by histones in locations unique to certain sequences, suggesting a particular program of gene expression following fertilization [53, 54]

Abbreviations PAF: Population attributable fraction CI: Confidence interval RR: Relative risk KNHES: Korea National Health Examination Survey

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