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Nicotine can harm brain development, which continues into the early to mid-20s

They produced a simple bar chart with a simple explanation of their findings: "Even with increasing restrictions on marketing, tobacco companies continue to compete fiercely for cigarette market share

For example, one can measure the plasma level of CYP1A2 enzyme activity, which should be reduced to a similar extent by switching from cigarette smoking to cMRTP use and smoking abstinence [37]

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Nicotine Tob Res (2017) 19(5):497505.10.1093/ntr/ntw228 4 MachaalaniRGhazaviEHintonTWatersKAHennessyA