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Thurmond was surrounded by doctors in white coats and Little League players in uniform as he announced the legislation, which bans all tobacco products, including smokeless ones

Table 3 summarise the role of non-CYP450 proteins involved in drug metabolism/transport and impact of cigarette smoking

Since the 1950s, tobacco smoke has been shown to impede DNA synthesis in the brains of newborn rats 1980s

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Studies in mice investigating the effects of e-cigarettes on different brain regions have found that e-cigarette exposure during pregnancy can alter the transcriptome of the frontal cortex (1316 mg/mL nicotine), increase global DNA methylation within the brain (1316 mg/mL nicotine), and dysregulate gene expression in the hippocampus (13 mg/mL nicotine) [176]