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To study the dynamics of insulin release, L-arginine (Merck, 1 g/kg body weight dissolved in 0.9% NaCl) was injected ip in animals fasted for 14 h to depolarize the -cell [40, 90] and thus elicit the secretion of insulin from the readily releasable pool (RRP) of insulin granules

For constipation, osmotic or stimulant laxatives may be used when dietary measures are insufficient, whereas loperamide or probiotic supplementation may be considered for persistent diarrhea

PMID: 13 BachD.NaonD.PichS.SorianoF

10.1016/j.jcis.2013.03.041 [3] Law K-Y

[17] [18] Patients should consult their healthcare provider before using these medications regularly