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1,2 Cigarette smoking contributes to many of the major causes of death in older adultsincluding cardiac disease, cancer, cerebrovascular disease, and dementiaand over 70% of all smoking-related deaths occur in smokers over the age of 60

Since cigarette smoking is a risk factor for developing atherosclerosis, the current study investigated the effects of cigarette smoke extract (CSE) on different events like expressions of genes involved in lipid influx and efflux, lipophagy, etc., that play vital roles in foam cell formation

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We had mostly the exact measurements, a difference of 1 mm was averaged for discrepancies, and when higher, we involved a third reviewer