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While the causes of this condition are complex, recent research has suggested that excess vitamin B12 intake may play a significant role

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High abdominal pressure at 25, 30, 40, or 50 mmHg was maintained until sacrifice at 60 min (25 mmHg), 30 min (30 mmHg, 40 mmHg), or 15 min (50 mmHg)

Singh et al., 2004