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Developed by Pfizer, it functions as a partial nicotine receptor agonist, meaning it binds to nicotine receptors in the brain and activates them to a lesser extent than nicotine itself
(2026a)
The gas phase of cigarette smoke include traces of acetaldehyde, methane, hydrogen cyanide, nitric acid, acetone, acrolein, ammonia, methanol, hydrogen sulfide, hydrocarbons, gas phase nitrosamines, carbonyl compounds and toxic metals including sodium, mercury, iron, arsenic, cadmium, and cobalt [29]
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