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The researchers also found that genes related to circadian rhythms (the body clock) were changed in mice exposed to e-cigarettes

[21] Prenatal exposure to tobacco smoke is associated with a higher risk of attention deficit hyperactivity disorder (ADHD) in children, though it remains unclear whether the relationship is causal or reflects shared genetic and familial factors between parent and child

Smoking increases plaque formation in blood vessels

Thus, hookah awareness/control should be more robust and systematic, but more importantly, further studies need to be conducted to better understand its negative health consequences and the mechanisms inducing such effects