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DOI: 10.1093/molbev/msu154 Biodiversity / Biogeography / Faunistics etc

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An increased inflammation response due to oxidative stress, and increased host susceptibility (both of which are discussed above)

Although multiple risk factors, including environmental, hormonal, genetic and viral factors, have been implicated in the pathogenesis of lung cancer in never smokers, no clear-cut dominant factor has emerged that can explain the relatively high incidence of lung cancer in never smokers and the marked geographic differences in gender proportions

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