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Be sure to talk with your doctor about the risks and benefits of these medications

Smoking status was defined as a categorical variable according to age at smoking initiation and total PY for the main analyses

Social Impact: Tobacco addiction is often stigmatized and leads to social isolation, whereas caffeine addiction is generally more socially acceptable and is even encouraged in some social settings

Check out our selection of non-tobacco chew flavors here, including both dip pouches and long cut options, all containing zero nicotine, zero tobacco, and loads of delicious flavor

Big Duke is for use by adults 21+ in the US who use tobacco and nicotine products