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[220] The study's authors dubbed it "The Charlie Sheen Effect", with commenters noting "Charlie Sheen did more for HIV education than most UN events do." [221] Sheen spoke out for HIV prevention, sharing the studies on social media, tweeting "Honored, humbled, inspired, hopeful." [222] Charity work Sheen was the 2004 spokesperson for the Lee National Denim Day breast cancer fundraiser that raised millions of dollars for research and education regarding the disease