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In addition, the thinness of the stratum corneum makes the epidermal barrier a very flexible structure, capable of carrying out its functions without limiting the movement of the organism.4 An alteration of the epidermal barrier that prevents it from carrying out its functions exposes the organism to physical, chemical, and biological aggressions leading to transepidermal water loss

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With the evolution of electronic cigarettes comes an increase in product variability, including chemical composition

Intentional cigarette burns, on the other hand, are typically circular in pattern

That is why such a tiny reservoir lasts so long