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The nicotine in tobacco can add a stimulating element to the experience, while the cannabinoids in cannabis contribute to the overall psychoactive and medicinal effects

When looking at the nicotine levels in the bloodstream of smokers and vapers, smokers had on average 30 nanograms of nicotine per millilitre of blood, compared to vapers 15 ng/ml

because of the changes that nicotine makes to their developing brains

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