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"Usually, there is cause for the lesion, for instance, chronic irritation from tobacco, a jagged tooth or grinding of the teeth, which can lead to temporary red or white patches in the mouth." However, if those issues are addressed by tobacco cessation, tooth removal/filing or a mouth guard, and the lesion remains after a few weeks, its time to take another look, she adds

The health behaviors of the subjects were exercise (weight-bearing exercise over 30 min/days: 0 times per week

This results in a chronic localized irritation

For most tests, it is recommended that you don't consume anything but water for 8, 12, or even 14 hours before the test