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The underappreciated role of epithelial mesenchymal transition in chronic obstructive pulmonary disease and its strong link to lung cancer
Nature 402:309313
These nerves are activated by a wide range of stimuli, including food extracts (capsaicin, wasabi, ginger, allicin, mustard oil), environmental irritants (vehicle exhaust, air pollution, tobacco smoke, burning vegetation), endogenous inflammatory mediators (prostaglandin E 2 , bradykinin), and acid (Mohammed et al., 1993
Over the next decade or so, from 1977 to 1988, roughly a third of Americans were smokers
